منابع مشابه
The binding site of rabbit hepatic lectin.
A hepatic lectin responsible for the clearance of desialylated serum glycoproteins was immobilized on Sepharose and the binding site was examined by a competitive binding assay using a 3H-labeled precursor blood group Ii glycoprotein and various glycoproteins, polysaccharides monosaccharides, and glycosides as inhibitors. The binding site is relatively small, involving a terminal sugar containi...
متن کاملThe binding site of chicken hepatic lectin.
The binding site of the chicken hepatic lectin involved in the clearance of N-acetylglucosamine-terminated serum glycoproteins was explored by a competitive binding assay using 3H-labeled agalacto-orosomucoid and various glycoproteins, polysaccharides, monosaccharides, and glycosides as inhibitors. The binding site is relatively small, involving a terminal nonreducing DGlcNAc structure with an ...
متن کاملSteady state and kinetic analysis of the binding of asialoorosomucoid to the isolated rabbit hepatic lectin.
The binding of 125I-asialoorosomucoid and the isolated rabbit hepatic lectin were studied at 0 degrees C. The steady state binding data were analyzed both by a direct curve-fitting procedure that utilizes nonlinear least squares regression analysis, and by conventional Scatchard plot analysis. Two classes of binding sites, present in approximately equal concentrations, were detected by both ana...
متن کاملSelective binding of N-acetylglucosamine to the chicken hepatic lectin.
Among Ca2+-dependent (C-type) animal lectins, the chicken hepatic lectin (CHL) is unique in displaying almost complete selectivity for N-acetylglucosamine over other monosaccharide ligands. The crystal structures of the carbohydrate-recognition domain (CRD) from serum mannose-binding protein (MBP) and of a complex between the CRD from liver MBP and the methyl glycoside of N-acetylglucosamine we...
متن کاملLectin-Binding Patterns in the Microenvironment of the Mouse Developing T-Cells
Glycoconjugates and their programmed changes during the course of development in the cell-surface as well as in the extracellular matrix, are known to affect cell differentiation, cellular interaction and other developmental phenomena during embryogenesis. The purpose of this study was to localize N-acetylgalactosamin as well as fucose-containing glycoconjugates in situ during thymus developmen...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1979
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)50739-0